The effect of prednisolone in patients with total hip arthroplasty

Preoperative effects of single high dose prednisolone in patients with total hip arthroplasty

Status

Recruiting

Phases

Phase 3

Study type

Observational

Source

IRCT

Registry ID

IRCT20200118046174N3

Enrollment

Registered

2021-03-01

Start date

2020-09-10

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of prednisolone on hip joint fractures leading to total hip arthroplasty. Idiopathic aseptic necrosis of bone

Interventions

Intervention 1: the intervention group will receive 125mg intravenous methylprednisolone acetate as an anti-inflammatory agent 12 hours before surgery as a single dose. methylprednisolone is a moderat

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: patients who are candidate for primary hip arthroplasty all the patients with avascular necrosis of femoral head all the patients with femoral neck fracture who are candidate for primary hip arthroplasty all the patients with severe hip joint osteoarthritis who are candidate for primary hip arthroplasty

Exclusion criteria

Exclusion criteria: Multiple trauma patients with fractures in different areas, Patients who are not candidates for standard surgery. Patients with a history of renal failure, liver, gastric ulcer, pregnancy, lactating women, history of corticosteroids Patients under 18 years of age, patients taking corticosteroids or opioids, patients with diabetic neuropathy and patients with heart failure, patients with poor control of diabetes mellitus (Poor control DM) Also, patients with poor control of high blood pressure are excluded from the study.

Design outcomes

Primary

Measure	Time frame
Patients after surgery underwent pain intensity assessment with a score of one to ten,Sleep quality assessments are completed by completing a psqi questionnaire, commissioning assessment, length of stay, and other demographic findings. Timepoint: At intervals of 2 weeks, 6 weeks, 12 weeks and 24 weeks. Method of measurement: In all patient visits, X-rays are performed in 2 directions and the graphs are checked by the senior orthopedic assistant. Patients are also examined at all times by an orthopedic assistant for R / O infection.	—

Measure

Time frame

Patients after surgery underwent pain intensity assessment with a score of one to ten,Sleep quality assessments are completed by completing a psqi questionnaire, commissioning assessment, length of stay, and other demographic findings. Timepoint: At intervals of 2 weeks, 6 weeks, 12 weeks and 24 weeks. Method of measurement: In all patient visits, X-rays are performed in 2 directions and the graphs are checked by the senior orthopedic assistant. Patients are also examined at all times by an orthopedic assistant for R / O infection.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoud Ghasemi

Tehran University of Medical Sciences

Dr.masoud.ghasemi.ortho@gmail.com.com23121297

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026