Diabetic nephropathy. Drug or chemical induced diabetes mellitus with diabetic nephropathy
Conditions
Interventions
Intervention 1: Intervention group: Patients in the case group are treated with allopurinol 100 mg daily. Intervention 2: Control group: Patients in the control group receive one placebo daily.
Sponsors
Shahre-kord University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 24-hour urine protein greater than 150mg / dl Uric acid between 6 and 15 Informed patient satisfaction The severity of diabetic nephropathy is similar in both groups Passive urine sedimentation
Exclusion criteria
Exclusion criteria: Patients treated with allopurinol Patients with significant renal failure (Cr> 3 mg / dl) or (GFR <25cc / min)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum uric acid level. Timepoint: After 3 and 6 months after starting the study. Method of measurement: Test.;GFR (Glomerular filtration rate). Timepoint: After 3 and 6 months after starting the study. Method of measurement: Formula.;24-hour urine protein content. Timepoint: After 3 and 6 months after starting the study. Method of measurement: 24-hour urine test.;Serum creatinine level. Timepoint: After 3 and 6 months after starting the study. Method of measurement: Test.;Serum urea level. Timepoint: After 3 and 6 months after starting the study. Method of measurement: Test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaeed Mardani
Shahre-kord University of Medical Sciences
Outcome results
None listed