cycloserine effect on neuropathic pain decreasing

Assessment of cycloserine effect on neuropathic pain after lumbar disc herniation surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200115046150N1

Enrollment

Registered

2020-09-12

Start date

2020-03-20

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar disc herniation. Nerve root and plexus compressions in intervertebral disc disorders

Interventions

Intervention 1: Intervention group: Cycloserine 250 g capsules are given to all members of the intervention group 2 hours before the start of surgery orally and in a single dose. Intervention 2: Contr

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age 18-70 years old BMI 19-24 Having informed consent Adaptation of clinical signs and symptoms to imaging findings

Exclusion criteria

Exclusion criteria: Candidate patients for laminectomy discectomy

Design outcomes

Primary

Measure	Time frame
Lumbar pain. Timepoint: 6,12,18,24 hours post operation. Method of measurement: visual analogue scale.	—

Secondary

Measure	Time frame
Morphine intake. Timepoint: 6,12,18,24 hours post operation. Method of measurement: The volume of drug injected into the cc.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPouria Basiry

Alborz University of Medical Sciences

pouriabasiry@gmail.com+98 26 3256 3324

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026