The effect of magnesium supplements on polycystic ovarian syndrome (PCOS)

The effect of magnesium supplements on clinical and metabolic variables in women with polycystic ovarian syndrome (PCOS)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200115046147N1

Enrollment

Registered

2020-02-01

Start date

2020-01-28

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovarian syndrome (PCOS).

Interventions

Intervention 1: Intervention group: In the magnesium group, magnesium oxide supplement made by Galen's company in the form of 250 mg a day for two months will be given to patients and in the control g

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Patients with polycystic ovary syndrome based on the Rotterdam Diagnostic Criteria2. Satisfaction with attending the study3. Satisfaction to continue cooperation4. Magnesium does not have a high base normal.5. There is no history of electrolyte abnormalities associated with potassium or calcium in the patient.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Changes in Insulin Resistance Index (HOMA-IR). Timepoint: FBS and serum insulin are re-administered to patients at baseline and after 2 months of treatment (end of treatment). Method of measurement: ice.Patients receive fasting insulin for a 12-hour fasting blood sample to measure fasting blood sugar (for diabetes screening).	—

Secondary

Measure	Time frame
Weight Loss and Blood Glucose and Lipid Profile and Blood Pressure and Menstrual Cycle Adjustment in Magnesium Supplemented Patients. Timepoint: After 2 months of treatment (end of treatment), weight, waist circumference, blood pressure, menstrual pattern and serum levels of FBS, TG, CHOL, LDL, HDL and insulin are monitored again for two months after completion. Patients will be monitored for clinical symptoms including menstruation, weight, waist circumference and blood pressure. Method of measurement: The pattern of menstrual periods is recorded in a questionnaire designed for the duration and duration of bleeding during the menstrual cycle. After fasting for 12 hours, a blood sample was taken to measure fasting blood sugar (for diabetes screening), fasting insulin and Mg levels, as well as TG, CHOL, HDL and LDL. People are included in the study who do not have high normal magnesium levels. Weight in fasting, without shoes, with minimal clothing and measured using the Seca Digital Balance with a accuracy of 0.1 kg. Height is measured with the help of a tape measure with a accuracy of 0.1 cm. BMI is calculated by dividing the weight in kilograms by the power of 2 heights per meter. Waist circumference greater than 5 cm above the navel and hip circumference less than 5 cm below the navel are measured with tape measure. Patients' blood pressure is measured and recorded with a single device.	—

Measure

Time frame

Weight Loss and Blood Glucose and Lipid Profile and Blood Pressure and Menstrual Cycle Adjustment in Magnesium Supplemented Patients. Timepoint: After 2 months of treatment (end of treatment), weight, waist circumference, blood pressure, menstrual pattern and serum levels of FBS, TG, CHOL, LDL, HDL and insulin are monitored again for two months after completion. Patients will be monitored for clinical symptoms including menstruation, weight, waist circumference and blood pressure. Method of measurement: The pattern of menstrual periods is recorded in a questionnaire designed for the duration and duration of bleeding during the menstrual cycle. After fasting for 12 hours, a blood sample was taken to measure fasting blood sugar (for diabetes screening), fasting insulin and Mg levels, as well as TG, CHOL, HDL and LDL. People are included in the study who do not have high normal magnesium levels. Weight in fasting, without shoes, with minimal clothing and measured using the Seca Digital Balance with a accuracy of 0.1 kg. Height is measured with the help of a tape measure with a accuracy of 0.1 cm. BMI is calculated by dividing the weight in kilograms by the power of 2 heights per meter. Waist circumference greater than 5 cm above the navel and hip circumference less than 5 cm below the navel are measured with tape measure. Patients' blood pressure is measured and recorded with a single device.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShabnam Shahmoradi

Zanjan University of Medical Sciences

ashkanghadimi23@gmail.com+98 24 3344 0932

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026