Formulation and clinical evaluation of muccoadhesive gel containing licorice based nanoniosomes for treatment of oral ulcers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200115046143N1

Enrollment

Registered

2020-01-26

Start date

2020-06-21

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral ulcers. Stomatitis and related lesions

Interventions

Intervention 1: Intervention group will receive niosomal mouthwash Licorice extract three times each half hour before meals for one week. Intervention 2: Control group: Primary oral care, as well as t

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Definite diagnosis of mild to moderate aphtous or mucositis by a dental specialist Absence of other skin diseases such as psoriasis No infection in the affected area

Exclusion criteria

Exclusion criteria: Diabetic patients with heart failure Pregnancy during the study Side effects that are not tolerated by the patient Immune deficiency Malignant diseases

Design outcomes

Primary

Measure	Time frame
Incidence and severity of oral ulcers. Timepoint: Before and up to a week after the intervention. Method of measurement: World Health Organization Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Yaser Vafaei

Hamedan University of Medical Sciences

y.vafaei@umsha.ac.ir+98 81 3838 1590

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026