The effect of phenobarbital, topiramate, and levothiracetam on neonatal seizures

Comparison of the effects of phenobarbital, topiramate and levotiracetam in the treatment of neonatal seizure

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200115046137N1

Enrollment

Registered

2020-08-05

Start date

2020-08-22

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal seizures. Convulsions of newborn

Interventions

Intervention 1: Intervention group: Phenobarbital 15mg tablet of Hayan Company with a dose of 5mg / kg / day / bid. Intervention 2: Oral Topiramate tablets 25 mg by Hayan Company with a dose of 3 mg /

Eligibility

Sex/Gender

All

Age

1 Days to 28 Days

Inclusion criteria

Inclusion criteria: All infants who had seizures after birth

Exclusion criteria

Exclusion criteria: Babies who were hospitalized for other reasons, such as apnea or thrush

Design outcomes

Primary

Measure	Time frame
Seizure type. Timepoint: Every month. Method of measurement: Clinical history.;Frequent seizures. Timepoint: Every month. Method of measurement: Clinical history.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Leila Islamian Ghadim

Tabriz University of Medical Sciences

l.eslamiyan@gmail.com+98 41 3333 6335

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026