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Radioprotective effect of ginseng in thyroid cancer patients

Evaluating the protective effect of oral ginseng in patients with thyroid cancer following administration of high levels of radioactive iodine by measuring micronuclei and some biochemical factors

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200115046136N1
Enrollment
80
Registered
2020-07-21
Start date
2020-01-29
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyroid cancer. Malignant neoplasm of thyroid gland

Interventions

Intervention 1: Intervention group 1: The group received one capsule containing 500 mg of Korean Ginseng (Panax Ginseng) from Isfahan Ponic Medicines Company, completely herbal with no chemical additi

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients between the ages of 30 and 60 who had thyroid cancer and underwent thyroid surgery. Patients who first receive radioactive iodine.

Exclusion criteria

Exclusion criteria: People who have undergone radiotherapy or chemotherapy in the last year. People with certain genetic diseases. People taking medications for heart and kidney failure, and those who take Warfarin anticoagulants definitively. People who smoke. People who are radiant People who have taken ginseng in the last month.

Design outcomes

Primary

MeasureTime frame
The level of micronuclei in lymphocytes of patients. Timepoint: At baseline (before intervention) and 48 hours after treatment. Method of measurement: Examination of lymphocytes of patients under the microscope after laboratory procedures.

Secondary

MeasureTime frame
Total antioxidant capacity. Timepoint: Before treatment and 48 hours after treatment. Method of measurement: Using the ELISA 96 kit.;Ischemic modified albumin. Timepoint: Before treatment and 48 hours after treatment. Method of measurement: Using the ELISA method.;The rate of malondialdehyde production in the process of oxidative stress. Timepoint: Before treatment and 48 hours after treatment. Method of measurement: Using the ELISA method.;Evaluation of hepatic Alanine transaminase. Timepoint: Before treatment and 48 hours after treatment. Method of measurement: Using the ELISA method.;Evaluation of hepatic enzyme Aspartate aminotransferase. Timepoint: Before treatment and 48 hours after treatment. Method of measurement: Using the ELISA method.;Blood urea nitrogen test. Timepoint: Before treatment and 48 hours after treatment. Method of measurement: Using the ELISA method.;Evaluation of Creatinine level. Timepoint: Before treatment and 48 hours after treatment. Method of measurement: Using the ELISA method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Reza fardid

Shiraz University of Medical Sciences

rfardid@sums.ac.ir+98 71 3227 0238

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026