Relapsing-remitting multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Recurrent-relapsing MS patients Disability level by Expanded Disability Status Scale = 6 (EDSS) Age between 20-35 years Able to write and read Muscle strength should be three or more in quadriceps and hamstrings muscles No history of anemia No depression according to Patient Health Questionnaire-9 (PHQ-9). No history of Diabetes No history of hypothyroidism No illnesses that increase fatigue, such as myasthenia gravis Not having disruptive spasticity in doing exercises No history of surgery or fracture No history of drug use in the past 6 months No history of cardiopulmonary diseases Complaints of fatigue that cause Disturbance in daily activities (should distinguish between extreme daytime sleepiness and fatigue).
Exclusion criteria
Exclusion criteria: Inadequate data recording Decreasing one's motivation (not wanting to continue cooperation and intentionally declare score 13 in the fatigue questionnaire) Patient Unables to learn the process
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Fatigue following rhythmic full squats, which is an independent variable , and based on the patient's self-expression is assessed using the BORG questionnaire, which has a range of 0-20, and when a person reaches a somewhat hard level, which is equivalent to 13 the full squat operation will not continue. 2. Kinesiotape, which is an independent nominal variable. 3. Multiple sclerosis, which is an independent nominal variable, relapsing remitting type of MS, which has been referred to us by a neurologist. Timepoint: At first, the participant's knee joint was measured with the help of a goniometer, and then he was asked to perform a full rhythmic squat until the moment, according to the BORG questionnaire at level 13, which is actually somewhat hard. The participant's knee position was then re-measured to assess changes in position sense error following rhythmic full squats. In the next step, the kinesiotape was first applied to three of the four heads of quadriceps muscle, and then the patient's knee condition was measured again to asses position sense errors following therapeutic intervention (taping). In the final stage, the person performed a rhythmic full squat protocol on the muscle and the kinesiotape applied on muscle to check for changes in position sense errors following fatigue associated with taping. Method of measurement: Kinesiological tape to examine its therapeutic effect in compense participant's fatigue and its effect on position sense and using a standard goniometer to assess the patient's position sense (reconstruction from 90 degrees to 45 degrees of knee flexion). | — |
Secondary
| Measure | Time frame |
|---|---|
| Position sense (including absolute, variable, and constant errors in angle reconstruction) that is a continuous dependent variable and is measured by the variance of the reconstructed angle. it measures with software and Goniameter and camera. Timepoint: Before and after performing the full squat protocol, after attaching the kinesiotape on the quadriceps muscle, and finally after performing the full squat protocol while the tape is attached to the muscle. Method of measurement: To test the position sense, a 16-megapixel Canon camera with a camera lens distance from the patient (80 cm) and a camera height from the ground (70 cm) was first placed. using markers on land marks was then performed on standard areas (greater trochanter of femur, lateral condyle offemur, head of the fibula, and lateral malleolus of the dominant limb). The patient then sat on the edge of the bed with his eyes closed so that his knees were at 90 degrees of flexion and the opposite leg was fixed on an adjustable, motionless stand. With a standard goniometer, the fixed arm of goniameter was placed on the thigh and the movable arm of goniameter was placed on the leg (fibula), the desired angle (about 45 degrees) was determined for the patient, so that the person should test this angle without a manual contact. It was kept for 5 seconds and then the patient was asked to return to the starting position (90 degree angle). The patient was then asked to raise his legs from 90 to 45 degrees with his eyes closed, and whenever he felt that his knee had been raised from 90 to 45 degrees, he would use a laser to flash on the front wall. The moment the laser light was seen, the reconstructed image was immediately photographed. The reconstruction was performed four times with a 5-second break between each repetition. Images were analyzed by the software in Excel environment and changes in the absolute, variable and constant errors of position sense were calculated. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences