Effect of fibrinogen on bleeding during pelvic surgery

The Effect of Prophylactic Fibrinogen Infusion on intraoperative bleeding during Pelvic Surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200109046064N1

Enrollment

Registered

2020-02-11

Start date

2020-02-20

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pelvic Surgery. Multiple fractures of lumbar spine and pelvis

Interventions

Intervention 1: Intervention group: Before surgery, one gram of prophylactic fibrinogen infusion (made by the Marburg factory in Germany) is performed in 50 ml of normal saline within five minutes aft

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients candidate for non-emergency pelvic surgery undergoing general anesthesia Satisfaction with study participation Age between 18-60 BMI<30 The preoperative fibrinogen level should be 2-4 g/lit

Exclusion criteria

Exclusion criteria: cardiovascular, liver, kidney, coagulation and hypertension disorders, diabetes and tumors in surgical areas. History of use the Beta-Blocker, Calcium Blocker, Digoxin, Tricyclic Antidepressants, Anti-Coagulant and Clonidine A history of alcohol, drug and drug abuse

Design outcomes

Primary

Measure	Time frame
Plasma fibrinogen. Timepoint: Before and after surgery. Method of measurement: Based on the patient's blood laboratory results.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Charousaie

Iran University of Medical Sciences

drch128@gmail.com+98 21 8214 1600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026