osteoarthritis.
Conditions
Interventions
Intervention 1: Intervention group 1: 40 mg curcumin tablet administered by Exir Nano Sina Pharmaceutical Company once daily. Intervention 2: Intervention group 2: Talental 480 mg tablet administered
Sponsors
Sabzevar University of Medical Sciences
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Knee osteoarthritis diagnosed by radiographic evidence and medical expert Knee pain more than two months Acceptable cognitive ability based on a brief cognitive test tool (score of 7 and above) No history of surgery related to the disease (eg replacement and joint repair) Non-injection of the drug into the knee joint within 30 days prior to intervention or schedule for injection until the end Study period
Exclusion criteria
Exclusion criteria: Taking narcotic drugs History of gallbladder and liver disease any surgery in the next 2 weeks Blindness and deafness and inability to communicate severe and untreated diseases Use of psychotropic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain, stiffness and knee joint function based on the WOMAC questionnaire. Timepoint: In 5 steps at the beginning of the experiment and at intervals of one week to one month. Method of measurement: WOMAC questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain reduction. Timepoint: 5 times: 1 before intervention and 4 times after intervention with weekly intervals for 4 weeks. Method of measurement: WOMAC questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRaha Salehabadi
Sabzevar University of Medical Sciences
Outcome results
None listed