The Efficacy of Cassia Fistula syrup on functional chronic constipation in chronic kidney disease

Evaluating the Efficacy of Cassia Fistula syrup on functional chronic constipation in chronic kidney disease (CKD) patients in comparison with the Lactulose (A Randomized Clinical Trial)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200105046009N6

Enrollment

Registered

2022-06-02

Start date

2022-06-06

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: chronic kidney disease. Condition 2: functional chronic constipation. Chronic kidney disease (CKD) Constipation

Interventions

Intervention 1: Intervention group: This group is given 30 cc of Cassia Fistula syrup (SANABEL DAROU Co.) daily divided into 3 doses for 14 days. Patients will be visited before the start of treatment

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Chronic kidney disease patients (CKD) with constipation Age between 18 to 80 years Having at least two criteria of ROME IV

Exclusion criteria

Exclusion criteria: History of sensitivity to Cassia Fistula History of active infection in last month History of any surgery on GI system Pregnant women Organic constipation

Design outcomes

Primary

Measure	Time frame
Frequency of defecation. Timepoint: Number of defecation per week. Method of measurement: Data gathering questionnaire.	—

Secondary

Measure	Time frame
Frequency of straining in defecation. Timepoint: Frequency of straining in defecation per week. Method of measurement: Data gathering questionnaire.;Feeling of incomplete emptying after defecation. Timepoint: Feeling of incomplete emptying after defecation per week. Method of measurement: Data gathering questionnaire.;Frequency of using manual maneuver. Timepoint: Number of applying manual maneuver for defecation per week. Method of measurement: Data gathering questionnaire.	—

Measure

Time frame

Frequency of straining in defecation. Timepoint: Frequency of straining in defecation per week. Method of measurement: Data gathering questionnaire.;Feeling of incomplete emptying after defecation. Timepoint: Feeling of incomplete emptying after defecation per week. Method of measurement: Data gathering questionnaire.;Frequency of using manual maneuver. Timepoint: Number of applying manual maneuver for defecation per week. Method of measurement: Data gathering questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Ali Mozaffarpur

Babol University of Medical Sciences

dr.mozaffarpur@mubabol.ac.ir+98 11 3219 4728

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026