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The effect of rhubarb (Rheum ribes L.) syrup in Children with acute diarrhea

The effect of rhubarb (Rheum ribes L.) syrup in Children 1to 6 years with acute diarrhea

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200105046009N5
Enrollment
96
Registered
2021-09-29
Start date
2021-10-01
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute diarrhea. Viral and other specified intestinal infections

Interventions

Intervention 1: Intervention group: Rhubarb syrup is prepared on the basis of USP 34 (USP simple syrup). USP simple syrup is based on water and sugar 66.7%. The syrup prepared is packaged in 120 ml am

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 6 Years

Inclusion criteria

Inclusion criteria: Children 1 to 6 years Acute diarrhea (loose stools for more than 3 times a day) in the last 72 hours Stool white blood cell count less than 5 / HPF in stool with or without mucus or blood Dehydration mild to moderate

Exclusion criteria

Exclusion criteria: More than three days have passed since the onset of diarrhea Children treated with antibiotics or antidiarrheal drugs in the last 3 days History of pneumonia, sepsis, meningitis, or toxic colitis during diarrhea Entamoeba histolytica cyst, Giardia lamblia trophozoite in stool exam Dysentery (infectious or non-infectious ) Dry milk consumption Severe malnutrition (weight less than 60% or weight/height less than 70%) History of known chronic diseases Any type of food allergy Use of probiotics Immunodeficiency Other infections including urinary tract infections

Design outcomes

Primary

MeasureTime frame
Time to recovery. Timepoint: Counting the days of diarrhea up to the normal defecation. Method of measurement: Recovery time from acute diarrhea is defined as the time interval between admission and cessation of diarrhea or the first normal bowel movements, which in the Bristol stool diagram is equivalent to a score below 5.

Secondary

MeasureTime frame
Duration of hospitalization. Timepoint: Counting the day of hospitalization (the days from hospitalization up to the discharge). Method of measurement: Counting the hospitalization days.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Ali Mozaffarpur

Babol University of Medical Sciences

seyyedali1357@gmail.com+98 11 3219 4728

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026