Concentrated sweet pomegranate extract by breastfeeding mothers, in jaundice

The effect of oral use of pomegranate concentrated juice by mothers on hyperbilirubinemia in neonate under phototherapy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200105046009N1

Enrollment

Registered

2020-05-28

Start date

2020-08-22

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal jaundice. Neonatal jaundice, unspecified

Interventions

Intervention 1: Intervention group: Mothers of neonats with hyperbilirubinemia. After entering the study , concentrated pomegranate extract is used three times a day until hospitalization.Sweet pomegr

Eligibility

Sex/Gender

All

Age

3 Days to 28 Days

Inclusion criteria

Inclusion criteria: Mothers of term infants (GA over 37 weeks) serum total bilirubin level of more than 15 mgr / dl over 48 hours of age breastfeed weighing more than 2,500 grams under phototherapy for the treatment of hyperbilirubinemia in the neonatal ward of Babol Shafizadeh Children's Hospital

Exclusion criteria

Exclusion criteria: Hemolytic disease (ABO, Rh incompatibility), G6PD deficiency in neonate Blood exchange in neonate Direct hyperbilirubinemia in neonate hyperbilirubinemia in neonate in the first 24 hours of life Systemic diseases such as liver, heart disease and hypothyroidism in neonate History of use of phenobarbital or other drugs or remedies in neonate sepsis in neonate respiratory distress in neonate Sensitivity to eating pomegranate juice in the mother

Design outcomes

Primary

Measure	Time frame
Neonates bilirubin levels in blood. Timepoint: daily after hospitalization. Method of measurement: Bilirubin is checked by Diazo (photometeric) method with Darman Faraz Kave kits made in Iran.	—

Secondary

Measure	Time frame
The duration of phototherapy. Timepoint: The days of phototherapy for neonate. Method of measurement: The duration (days) of phototherapy.;The duration of hospitalization. Timepoint: the duration of hospitalization of neonates. Method of measurement: The duration (days) of phototherapy.;The need for blood transfusions. Timepoint: during hospitalization. Method of measurement: Is blood transfusions performed or not?.	—

Measure

Time frame

The duration of phototherapy. Timepoint: The days of phototherapy for neonate. Method of measurement: The duration (days) of phototherapy.;The duration of hospitalization. Timepoint: the duration of hospitalization of neonates. Method of measurement: The duration (days) of phototherapy.;The need for blood transfusions. Timepoint: during hospitalization. Method of measurement: Is blood transfusions performed or not?.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Ali Mozaffarpur

Babol University of Medical Sciences

seyyedali1357@gmail.com+98 11 3219 4730

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026