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The effect of locally administered Sambucus ebulus gel 5% on the severity and extention of pruritus in hemodialysis patients

The effect of locally administered Sambucus ebulus gel 5% on the severity and extention of pruritus in hemodialysis patients

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191231045958N1
Enrollment
150
Registered
2020-04-12
Start date
2020-04-20
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pruritus in hemodialysis patients. Pruritus, unspecified

Interventions

Intervention 1: The aim of this study was to investigate the effect of locally administered sambucus ebulus gel 5% on the severity and extention of pruritus hemodialysis patients.Three groups of

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 18 years who have been undergoing hemodialysis for more than 3 months Patients who have had itching at least 3 times in the last 2 weeks Despite drug use in the last month of treatment, no evidence of improvement was observed Patients undergo hemodialysis 3 days a week for 3–5 hours per session Have no skin problems other than uremic itching Patients who gave their written consent to participate in the project Patients who do not use another method to reduce the severity of itching Lack of systemic diseases such as liver cholestatic, hepatitis B, HIV thyroid disorders and women who are not pregnant and breastfeeding Lack of cognitive impairments that cannot answer questions

Exclusion criteria

Exclusion criteria: If the patient undergoes kidney transplantation during the study If there is allergy to sambucus ebulus gel Patients who do not wish to continue the study for personal reasons Patients with a phosphorus test range of more than 6 and a PTH of more than 300

Design outcomes

Primary

MeasureTime frame
Pruritus. Timepoint: first visit-The fourth and eighth week after starting to use the gel. Method of measurement: 48-point scale for itching severity.

Secondary

MeasureTime frame
Skin dryness. Timepoint: first week, The fourth and eighth week after starting to use the gel. Method of measurement: Examination.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmohadese saberian

Mazandaran University of Medical Sciences

h_saberian@yahoo.com????????

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026