Condition 1: Blepharitis. Condition 2: Dry eye syndrome. Blepharitis Dry eye syndrome
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, in addition to the usual treatment of the control group, which includes chloramphenicol drop every 8 hours and betamethasone eye drop eve
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Blepharitis disease Age greater than or equal to 18 years OSDI test score greater than or equal to 22 Eyelid margin disease without severe inflammation SM tube test greater than or equal to 3 mm
Exclusion criteria
Exclusion criteria: Use topical eye treatments now or less than a month ago Receiving systemic treatments for eyelid diseases at the time of referral or one month before the visit Receiving any systemic treatment now or during the past month that affects tear secretion Use of contact lenses History of ocular burns or trauma Recent ocular surgery (less than 3 months ago) Anterior segment active disease Patients with acquired human immunodeficiency virus Patients with graft-versus-host disease Patients with rheumatic diseases, renal disease and sarcoidosis Diabetes Pregnancy and lactation Any dermatological or systemic disease that affects ocular surface Known drug allergies to Esmed kohl
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dry eye score in OSDI questionnaire. Timepoint: At the beginning of study (before the intervention) and 40 days after the intervention. Method of measurement: Fill out the OSDI Dry Eye Questionnaire.;Tear break up test. Timepoint: Measurement of tear dissolution time at the beginning of the study (before the intervention) and 40 days after application. Method of measurement: Using fluorescein moistened with saline solution, the average time elapsed before the initial dissolution of the tear is measured three times.;Basic tear secretion rate. Timepoint: Measurement of tear secretion at the beginning of the study (before the intervention) and 40 days after using Esmed kohl. Method of measurement: Strip meniscometry tube.;Corneal staining areas. Timepoint: Measurement of corneal staining areas at the beginning of the study (before the intervention) and 40 days after using Esmed kohl. Method of measurement: By an ophthalmologist with a slit lamp device and blue light shining on the cornea.;Blepharitis severity. Timepoint: Examination of the eyelid margin and blepharitis at the beginning of the study (before the intervention) and 40 days after the use of Esmed kohl. Method of measurement: Examination by an ophthalmologist with a slit lamp device and determining the mild, moderate or severe blepharitis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Hasani
Karaj University of Medical Sciences
Outcome results
None listed