Condition 1: Dry eye disease. Condition 2: Blepharitis. Other disorders of lacrimal gland Blepharitis
Conditions
Interventions
Intervention 1: Intervention group: The intervention group received a gel containing 5% tea tree oil for massage on the eyelid twice a day for four weeks. Intervention 2: Control group: The control gr
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age older than or equal to 18 years Ocular Surface Disease Index(OSDI) test score greater than or equal to 22 Eyelid margin disease without severe inflammation Strip Meniscometry (SM) Tube? test greater than or equal to 3-4 mm People who sign the informed consent form
Exclusion criteria
Exclusion criteria: People who are very old and difficult to get information from People who have received systemic treatment for eyelid disease at the time of admission or one month before admission Receive any systemic treatment now or during the past month that affects tear secretion People who wear contact lenses Recent ocular surgery (less than 3 months ago) Active disease in the anterior segment of the eyeball except dry eye (such as keratitis), Patients with HIV (human immunodeficiency virus), sarcoidosis, graft versus host disease with previous diagnosis Patients with rheumatic diseases, serious kidney disease (need for hemodialysis or history of kidney transplantation), diabetes, pregnancy, lactation, any dermatological or systemic disease that affects the surface of the eye known medication allergies to the drugs used in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index (OSDI) questionnaire score. Timepoint: Measurement of OSDI questionnaire score at the beginning of the study (before the intervention) and 28 days after the start of the gel containing tea tree oil and placebo. Method of measurement: Fill out the questionnaire.;Tear break up test. Timepoint: Measurement of tear break up test at the beginning of the study (before the intervention) and 28 days after the start of the gel containing tea tree oil and placebo. Method of measurement: Using fluorescein moistened with saline solution, the average time elapsed before the initial dissolution of the tear is measured three times.;The amount of tear basal secretion. Timepoint: Measurement of tear basal secretion at the beginning of the study (before the intervention) and 28 days after the start of the gel containing tea tree oil and placebo. Method of measurement: Strip Meniscometry Tube.;Corneal staining. Timepoint: Examination of corneal discoloration areas at the beginning of the study (before the intervention) and 28 days after the start of the gel containing tea tree oil and placebo. Method of measurement: By an ophthalmologist with a slit lamp and blue light to the cornea. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Hasani
Iran University of Medical Sciences
Outcome results
None listed