Skip to content

the effect of tamsulosin and tadalafil in response to treatment of patients with lower urinary tract symptoms

Comparison of the effect of tamsulosin and tadalafil in response to treatment of patients with lower urinary tract symptoms due to the severity of atherosclerosis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191230045943N1
Enrollment
200
Registered
2020-10-03
Start date
2020-09-30
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Atherosclerosis. Condition 2: Obstructive and urinary tract symptoms. Atherosclerosis Obstructive and reflux uropathy, unspecified

Interventions

Intervention 1: Intervention group: Treatment with tamsulosin 0.4 mg daily one alone- (Trade names, Flomax, others )- Patients before treatment, 4, 8 and 12 weeks after starting treatment (PVR, IPSS,

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 100 Years

Inclusion criteria

Inclusion criteria: Male patients referred to urology clinic with obstructive and urinary tract symptoms for at least 6 months Patients over 50 years of age

Exclusion criteria

Exclusion criteria: Male patients referred to urology clinic less than 50 years old PSA higher than 10 Urine residue 300ml or higher determined by ultrasound Receiving Finasteride during the last 3 months Receiving anti-androgen drugs History of pelvic surgery or radiotherapy History of lower urinary tract malignancy Lower urinary tract trauma Urinary retention Bladder stones Urinary tract infection that is determined by urine culture Urethral stricture Neurological disease affecting bladder function Secondary obstruction to the median lobe of the prostate Prostate cancer Liver or kidney failure Cardiovascular diseases such as significant angina that need to be checked by a cardiologist and CHF not compensated, recent MI and uncontrolled blood pressure treatment with nitrates Uncontrolled diabetes HbAlc> 9%

Design outcomes

Primary

MeasureTime frame
Treatment of obstructive and urinary tract symptoms. Timepoint: At one month intervals for three months. Method of measurement: Q max evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Akram Mirzaei

Tehran University of Medical Sciences

mirzaee.scholar@gmail.com+98 21 6634 8560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026