Squamous cell carcinoma. Other and unspecified malignant neoplasm of skin, unspecified
Conditions
Interventions
Initially, clinical images of the patient’s wound will be taken by the researcher using a mobile phone camera before any intervention. Then, in the first phase, a 0.5 mg/ml formulated methylene blue s
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Histopathologically confirmed diagnosis of squamous cell carcinoma (SCC) Provision of written informed consent to participate in the study Lack of willingness or eligibility for surgical excision or radiotherapy, or contraindication to intralesional medical treatments such as interferon-alpha or 5-fluorouracil (5-FU) Age more than 18 years Presence of multiple lesions
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding History of severe adverse reactions to medications Cardiovascular disease Thromboembolic disorders History of chronic arsenic exposure Immunodeficiency Presence of severe systemic illness Known allergy or hypersensitivity to methylene blue History of bleeding disorders or abnormal coagulation Severe inflammatory or dermatologic conditions in the treatment area
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound size. Timepoint: Measurement of wound dimensions before the intervention, one month after the intervention, and two months after the intervention. Method of measurement: Wound images will be analyzed using Healup image analysis software, and the area of the wound will be calculated. | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound recurrence. Timepoint: Measurement of wound dimensions before the intervention and three months after the completion of the intervention. Method of measurement: Wound images will be analyzed using Healup image analysis software, and the area of the wound will be calculated. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDaryoush Hamidi Alamdari
Mashhad University of Medical Sciences
Outcome results
None listed