Effect of PRP-Fibrin glue and Repairing gel in treatment of second-degree burn wounds

Treatment of second-degree burn wound with PRP-Fibrin glue and repairing gel

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191228045924N6

Enrollment

Registered

2023-11-12

Start date

2023-12-22

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn of second degree. Burn of second degree, body region unspecified

Interventions

Intervention 1: First intervention group: For 10 patients with second-degree burns, platelet-fibrin glue in the form of gel will be placed on the patient s wound. The number of times of use: use of fi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Confirmation of second-degree burns Having a body mass index of 18-35 No smoking, alcohol and drug addiction Not taking drugs that may interfere with wound healing, such as corticosteroids, immunosuppressive agents, and cytotoxic agents Not having concurrent diseases that may cause problems in wound healing, such as cancers, vasculitis, kidney, liver, and heart failures Informed consent of patients

Exclusion criteria

Exclusion criteria: The presence of a wound with an active infection requiring intravenous antibiotics or gangrene requiring amputation Failure to refer the patient to the mentioned center for follow-up and dressing change on more than two occasions

Design outcomes

Primary

Measure	Time frame
Visual Analog Scale changes for pain assessment. Timepoint: Every 48 hours for 8 weeks. Method of measurement: Pain will be evaluated by the visual analog scale system (VAS). The score is determined by measuring the distance (mm) between the no-pain anchor and the point that the patient marks, providing a range of scores from 0 - 10. A higher score indicates greater pain intensity.;The duration of recovery is the number of days it will take for the wound to heal. Timepoint: The interval from the beginning of the study (0 days) to wound healing. Method of measurement: Counting days.;Change from Baseline Wound Size (length and width) will be assessed in digital images taken of the wound. Timepoint: At the beginning of the study (0 days) and at the end of the eighth week of the intervention (8 weeks). Method of measurement: digital images and ruler.	—

Measure

Time frame

Visual Analog Scale changes for pain assessment. Timepoint: Every 48 hours for 8 weeks. Method of measurement: Pain will be evaluated by the visual analog scale system (VAS). The score is determined by measuring the distance (mm) between the no-pain anchor and the point that the patient marks, providing a range of scores from 0 - 10. A higher score indicates greater pain intensity.;The duration of recovery is the number of days it will take for the wound to heal. Timepoint: The interval from the beginning of the study (0 days) to wound healing. Method of measurement: Counting days.;Change from Baseline Wound Size (length and width) will be assessed in digital images taken of the wound. Timepoint: At the beginning of the study (0 days) and at the end of the eighth week of the intervention (8 weeks). Method of measurement: digital images and ruler.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Hasan Tavousi

Mashhad University of Medical Sciences

TavoosiH@mums.ac.ir+98 915 511 8717

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026