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Investigating the effect of repairing gel and platelet-fibrin glue in the healing of wounds

Increasing the effectiveness of platelet-fibrin glue in the healing of recalcitrant wounds by adding the repairing gel which has the approved components in wound healing

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191228045924N5
Enrollment
40
Registered
2023-07-10
Start date
2023-07-20
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Wound. Multiple open wounds, unspecified

Interventions

Intervention 1: First intervention group: 10 patients with chronic wounds, the classical treatment will be performed, and then platelet-fibrin glue in the form of gel will be placed on the patient's w

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Having a single wound on the body that has been at least 3 months old and has not been repaired by wound irrigation with normal saline and changing the dressing Having a body mass index of 18-35 Sign the informed consent by patient

Exclusion criteria

Exclusion criteria: Having concurrent diseases that may cause problems in wound healing, such as cancers, vasculitis, kidney and liver failure, and heart failure Taking certain drugs that may interfere with wound healing, such as corticosteroids, immunosuppressive agents, and cytotoxic agents

Design outcomes

Primary

MeasureTime frame
The amount of pain. Timepoint: It is measured after two days of changing the dressing. Method of measurement: Visual Analogue Scale.;The duration of recovery, which is the number of days it takes for the wound to heal. Timepoint: Every 24 hours (every day). Method of measurement: By visual observation.;Presence of inflammation and infection. Timepoint: Before the intervention and after the intervention every week for two month. Method of measurement: Clinical examination.;Quality of Life. Timepoint: Before the intervention and after the intervention. Method of measurement: Completing the SF36 questionnaire.

Secondary

MeasureTime frame
Reepithelialisation and wound closure. Timepoint: Every week for two month after dressing. Method of measurement: Clinical observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDaryoush Hamidi Alamdari

Mashhad University of Medical Sciences

hamidiad@mums.ac.ir+98 915 101 7650

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026