chronic obstructive pulmonary disease. Chronic obstructive pulmonary disease, unspecified
Conditions
Interventions
Intervention 1: Intervention group: nano-curcumin supplement, one capsule daily, each capsule contains 80 mg of curcumin in the form of nanomicelles, for 12 weeks, consumed with food, produced by Sina
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: • Adult age range (18-65 years). Smokers who have been smoking for at least 10 years. Confirmation of chronic obstructive pulmonary disease according to GOLD criteria. The patient has stages 3 and 4 of chronic pulmonary obstruction.
Exclusion criteria
Exclusion criteria: Patient with gallstones Infectious diseases Gastrointestinal problems such as malabsorption Other chronic diseases (such as cancer, kidney disease, diabetes, etc.). Long-term use of corticosteroid drugs and compounds, ie, more than 10 days of corticosteroid use per year. Use of any anticoagulant drugs such as heparin, aspirin, clopidogrel, dipyridamole, warfarin and ticlopidine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interleukin-6. Timepoint: beginning and end of supplementation. Method of measurement: ELISA.;Spirometry. Timepoint: beginning and end of supplementation. Method of measurement: Spirometere.;Anthropometric measurements. Timepoint: beginning and end of supplementation. Method of measurement: Bioelectric impedance device.;Blood pressure. Timepoint: beginning and end of supplementation. Method of measurement: sphygmomanometer.;Dietary intake. Timepoint: beginning and end of supplementation. Method of measurement: Food record form.;Physical activity. Timepoint: beginning and end of supplementation. Method of measurement: international physical activity questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRasoul Zarrin
Oroumia University of Medical Sciences
Outcome results
None listed