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The effect of Masport Botulinum toxin injection in reducing the recurrence of bulbar urethral stricture

The effect of Botulinum toxin Masport injection following internal urethrotomy indecrease of recurrence of bulbar urethral stricture

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191222045852N1
Enrollment
20
Registered
2023-10-29
Start date
2019-04-04
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bulbar Urethral Stricture. Other specified disorders of male genital organs

Interventions

Intervention group: men with bulbar stricture who were injected with botulinum toxin type A after surgery.Patients underwent spinal anesthesia and dorsal position lithotomy and underwent direct vision

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
19 Years to 70 Years

Inclusion criteria

Inclusion criteria: Men over 18 years Diagnosed with urethral stricture Who were candidates for surgery for bulbar stricture

Exclusion criteria

Exclusion criteria: Patients with stenosis length of more than 1.5 cm Spongiofibrosis Acute retention Multiple stenosis Stenosis due to lichen sclerosis Active urinary tract infections, Neurogenic bladder, Stenosis in the penile urethra or membranous History of benign prostatic hyperplasia Prostate cancer Pelvic radiotherapy Urethroplasty More than one internal urethrotomy Hypersensitivity reaction to any of the components of Botulinum Toxin Type A

Design outcomes

Primary

MeasureTime frame
Primary outcome: recurrence rate of urethral stricture. Timepoint: 3-6-9 months after the operation. Method of measurement: Questionnaire, examination, uroflowmetry.

Secondary

MeasureTime frame
Investigation of prostate symptoms. Timepoint: 3-6-9 months after the intervention. Method of measurement: Questionnaire, examination, uroflowmetry.;Investigation of surgical outcome. Timepoint: 3-6-9 months after the intervention. Method of measurement: Questionnaire, examination, uroflowmetry.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactkeshvar samadaee gelehkolaee

Mazandaran University of Medical Sciences

k-samadaee@alumnus.tums.ac.ir+98 11 3304 4000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026