Cutaneous leishmaniasis. Cutaneous leishmaniasis
Conditions
Interventions
Intervention 1: Intervention group: Standard treatment plus cream (topical medicinal product) containing extract of cotton plant is administered twice daily for 8 weeks. Intervention 2: Intervention g
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
6 Years to 60 Years
Inclusion criteria
Inclusion criteria: Proof of cutaneous leishmaniasis through smear The patients should not be less than 6 years old and not more than 60 years old The lesion size should be less than 3 cm The duration of the illness is less than 12 weeks No lesion on the face Not having any other anti-leishmaniasis medication in the past 4 weeks Don't be pregnant or breastfeeding Do not have severe skin disease such as eczema, psoriasis or chronic dermatitis of unknown origin Has no serious, chronic or malignant disease and is not under chemotherapy treatment Has 4 or less lesions in the body No travel history 6 months ago
Exclusion criteria
Exclusion criteria: The type of cutaneous leishmaniasis may be complicated, with complications such as a patient with mucosal leishmaniasis Having 5 lesions and more Lesions greater than 3 cm Subcutaneous nodules Regional adenopathy larger than 1 cm People with immunodeficiency Children under 6 years Women in Lactation and Pregnancy sporotrichoid leishmaniasis or satellite lesions Patients with ulcers on the face Patients with a history of drug allergy to antimony compounds Patients who have had more than three months since their first skin lesions appeared Patients who have used any method of treatment for cutaneous leishmaniasis during the past month Patients with a history of travel to other areas of leishmaniasis in the past 6 months as well as those of urban leishmaniasis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Leishmaniasis lesion area. Timepoint: Before treatment and then every week until healing or the eighth week. Method of measurement: Mathematical calculations with mm-square scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound healing time. Timepoint: End of treatment. Method of measurement: Time between start and end of treatment in days. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMajid Emtiazy
Yazd University of Medical Sciences
Outcome results
None listed