scleroderma. Systemic sclerosis [scleroderma]
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, patients use silver nanospray 4 times a day (every 6 hours) on the finger ulcers. Intervention 2: Control group: In the control group, pa
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged > 18 years 2. Patients with finger ulcers, caused by scleroderma, with mild to moderate severity (1-10 new ulcers in the fingers involving surface epithelial cells, the epidermis, the dermis, or the subcutaneous tissue) and without purulent discharge 3. Patients who signed our patient consent permission form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe finger ulcers (more than 10 new ulcers in the fingers, extensive tissue destruction with damage to muscle, supporting structures (eg, tendon, joint capsule) and bone, necrosis and gangrene) Patients who do not use the spray regularly
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The size of ulcers. Timepoint: weekly. Method of measurement: Length x Width: Measure the greatest length (head to toe) and the greatest width (side to side) using a centimeter ruler.;(DUS) digital ulcer score. Timepoint: weekly. Method of measurement: Length x depth of ulcer.;The healing time of ulcers. Timepoint: weekly. Method of measurement: Observing the appearance of the ulcer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intensity of pain in patients with ulcers. Timepoint: weekly. Method of measurement: visual analogue scale (VAS).;The quality of life of patients. Timepoint: weekly. Method of measurement: Health-Related Quality of Life (HRQOL) questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZinat Heidari
Mashhad University of Medical Sciences
Outcome results
None listed