Effect of co2 gas in treatment of eye dark circle

Evaluation of the effectiveness of Carboxytherapy in treatment of eye dark circle

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191219045826N1

Enrollment

Registered

2020-02-12

Start date

2019-01-24

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dark under eye circles.

Interventions

Twenty consecutive eligible patients with DECs selected to enter the study and received carboxytherapy as injection of once weekly intradermally 10 to 20 cc of CO2 gas at a rate of 20 cc per minute wi

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Symetrical eye dark circle Bilatral eye dark circle Age of 20 to 50 years old

Exclusion criteria

Exclusion criteria: Give treatment History of keloid formation Have systemic disease Botax injection since 6/m ago

Design outcomes

Primary

Measure	Time frame
Dark under eye circles. Timepoint: Befor gaz injection then 2 month after last injection. Method of measurement: visioface delta E scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAboozar Shafiei

Shiraz University of Medical Sciences

dr.a.shafeie55@gmail.com+98 71 4224 0028

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026