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Effects of Iranian propolis supplementation on chronic kidney disease

Effects of Iranian propolis supplementation on proteinuria, 24 hour urine, serum creatinine, prooxidant-antioxidant Balance, Glycemic indices, quality of life and blood pressure in patients with chronic kidney disease: a randomized, double-blind, placebo-controlled trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191218045798N1
Enrollment
44
Registered
2020-06-07
Start date
2020-07-22
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic kidney disease (CKD).

Interventions

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: The tendency to participate in the study Having stage 2 or 3 CKD according to eGFR of 30-89 ml/min per 1.73 m2 Aged 20-80 years old

Exclusion criteria

Exclusion criteria: BMI less than 18.5 or more than 35 kg/ m2 Kidney transplant recipients Pregnancy or breastfeeding Having any kind of allergy or asthma Receiving steroids or other immune system suppressors Taking herbals in the last 3 months Smoking, Being addicted, consuming alcohol or opioids Professional athletes Having chronic inflammatory disease (rheumatoid arthritis, IBD), severe depression, schizophrenia, severe liver failure, liver cirrhosis, cancers, severe infection

Design outcomes

Primary

MeasureTime frame
Improvement in kidney function ( proteinuria, 24 hour urine, serum creatinine ). Timepoint: at the beginning and end of the study. Method of measurement: 24-hour urine collection to measure 24-hour urine volume and proteinuria, Jaffe's method for measuring serum creatinine.

Secondary

MeasureTime frame
Prooxidant-antioxidant Balance. Timepoint: at the beginning and end of the study. Method of measurement: prooxidant-antioxidant Balance method.;Glycemic indices ( FBS, HbA1c, insulin ) and HOMA-IR index. Timepoint: at the beginning and end of the study. Method of measurement: biochemical assessment.;Quality of life. Timepoint: at the beginning and end of the study. Method of measurement: questionnaire.;Blood pressure. Timepoint: at the beginning and end of the study. Method of measurement: Mercury sphygmomanometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPaniz Anvari fard

Tabriz University of Medical Sciences

panizanvari@yahoo.com+98 41 3381 3665

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026