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The effect of L-carnitin as an adjunctive therapy in treatment of negative and positive symptom in schizophrenia

The effect of L-carnitin as an adjunctive therapy in treatment of negative and positive symptom in schizophrenia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191218045795N6
Enrollment
60
Registered
2023-01-16
Start date
2023-01-21
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia. Schizophrenia

Interventions

Intervention 1: Intervention group: The drug used is l-carnitine 1000 mg, which is given to the intervention group daily for eight weeks, which is completely similar to the placebo drug in terms of w

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: Not having severe major depression based on Beck Depression Test (BECK Total score<29 have received psychiatric drugs with a fixed dose during the last 3 months. be treated with one of the second generation antipsychotic drugs

Exclusion criteria

Exclusion criteria: Presence of another diagnosis based on DSM-5 Intellectual disability Received ECT in the past 2 months History of substance and drug use except nicotine and caffeine History of seizures

Design outcomes

Primary

MeasureTime frame
The score of positive and negative symptoms in the PANSS test. Timepoint: The beginning of the study, the end of the fourth week, the end of the eighth week. Method of measurement: Clinical interview based on PANSS.

Secondary

MeasureTime frame
Metabolic syndrome. Timepoint: The beginning and end of the study. Method of measurement: Measurement of height and weight, blood pressure and waist circumference through clinical examination and measurement of triglycerides and cholesterol through paraclinics.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNarges Shamsalizadeh

Sanandaj University of Medical Sciences

n.shamsalizadeh@muk.ac.ir+98 87 3366 4957

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026