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Comparison of the Effect of Classic and Goal-Directed Fluid Therapy on Liver Transplantation

Comparison of the Effect of Classic and Goal-Directed Fluid Therapy on Intraoperative Hemodynamic Criteria and Postoperative Complications of Liver Transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191214045735N1
Enrollment
100
Registered
2022-04-15
Start date
2020-10-01
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver transplant. Complications of liver transplant

Interventions

Intervention 1: Intervention group: goal-directed therapy. Patients in the intervention group will be monitored continuously for goal-directed fluid therapy. Goal-directed fluid therapy (GDFT) using m

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients need a liver transplant Age 18 to 80 years old Informed consent

Exclusion criteria

Exclusion criteria: Renewed liver transplant Patients who are candidates for surgery due to non-cirrhotic diseases Fulminant liver failure Weight less than 40 kg Need for emergency surgery Previous mental disorders Prisoners Patients undergoing clinical trial studies at the same time as this study Dissatisfaction with participating in the study

Design outcomes

Primary

MeasureTime frame
Incidence of complications in the studied patients. Timepoint: Before, during and zero, one, 12 hours after surgery when discharged from the intensive care unit and hospital and follow-up of the patient one month after discharge. Method of measurement: Clavien-Dindo classification criteria.

Secondary

MeasureTime frame
Mortality rate of studied patients. Timepoint: Before, during and zero, one, 12 hours after surgery when discharged from the intensive care unit and hospital and follow-up of the patient one month after discharge. Method of measurement: Based on follow-up (observation and telephone).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Bahman

Tehran University of Medical Sciences

dr.reza.bahman@gmail.com+98 21 6119 0008

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026