Effect of Melatonin on Coronary perfusion after primary percutaneous coronary intervention

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191214045726N1

Enrollment

Registered

2020-01-15

Start date

2020-01-21

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial infarction. ST elevation (STEMI) myocardial infarction of unspecified site

Interventions

Intervention 1: Intervention group: 3 mg melatonin given to patients with myocardial infarction before PPCI instead o

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Acute Myocardial infarction Age older than 18 years old PPCI for the first 6 hours STEMI evidence in patient electrocardiogram Blockage of one of the major coronary arteries Verbal desire and written patient satisfaction to participate in the study

Exclusion criteria

Exclusion criteria: Chronic renal failure A history of autoimmune disease Atrial fibrilation Pregnancy or breast feeding

Design outcomes

Primary

Measure	Time frame
Changes in coronary artery perfusion. Timepoint: Determination of coronary perfusion before PPCI and within 40 days after PPCI. Method of measurement: Angiography and echocardiography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahid Eslami

Shahid Beheshti University of Medical Sciences

veslami3525@yahoo.com+98 21 4087 2207

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026