Melasma. Chloasma
Conditions
Interventions
Intervention 1: Intervention group: One side of the face is injected with Tranexamic acid 50 mg / ml and Ascorbic acid 50 mg / ml is given intradermally every other week for 12 weeks. Intervention 2:
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Women at the range of 18 to 50 years old patients with symmetrical bilateral melasma
Exclusion criteria
Exclusion criteria: Patient who is pregnant or in lactation period Patient who had taken oral contraceptive pill in 12 months ago Patient who has history of coagulopathy and thrombotic disorder Patient who ia taking anticoagulant and antiepileptic drug Patient who has sensitivity to tranexamic acid Patient who has history of treatment for melasma during 1 month ago Patient who has active facial herpes simplex virus infection Patient who has facial wart
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma area and severity index. Timepoint: Melasma area and severity index measured at base of trial and 4, 8, 12 and24 weeks of trial. Method of measurement: Melasma area and severity index. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction. Timepoint: Measuring of patient satisfaction in 4, 8, 12 and 24 weeks of trial. Method of measurement: Satisfaction percentage questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDoctor Seyedeh Nasrin Molavi
Ahvaz University of Medical Sciences
Outcome results
None listed