Evaluation of the efficacy and safety of doxycycline in combination with standard treatment in Covid-19 patients.. COVID-19, virus identified
Conditions
Interventions
Intervention 1: Intervention group: includes 30 patients who receive doxycycline every 12 hours for 7 days along with standard treatment. Intervention 2: Control group: Includes 30 patients receive pl
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Minimum age 18 and maximum age 80 years Signing up the informed consent form Do not take ?doxycycline during the past 5 days Patients suspected of covid-19 based on clinical signs and manifestations of CT scan Candidate for outpatient treatment
Exclusion criteria
Exclusion criteria: Patients hospitalized Patients with hemodynamic instability Patients with a history of allergic reaction or allergy to doxycycline Second and third trimesters of pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improve clinical symptoms including fever, shortness of breath, cough. Timepoint: Before starting the intervention and Days 1, 3, 7 and 14. Method of measurement: Questionnaire.;Blood o2 saturation. Timepoint: Before starting the intervention and Days 3 and 7. Method of measurement: Pulse oximetry device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality. Timepoint: Day 14. Method of measurement: Questionnaire.;Hospitalization. Timepoint: Days 7 and 14. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZohreh Akhoundi Meybodi
Yazd University of Medical Sciences
Outcome results
None listed