Covid-19. COVID-19, virus identified
Conditions
Interventions
Intervention 1: Intervention group: includes 50 patients who receive magnesium sulfate inhaled (5 cc of a 20% injectable vial or 2 cc of a 50% injectable vial will be diluted by 50 cc distilled water
Sponsors
National Research Institute of Tuberculosis and Lung Diseases(NRITLD), Masih Daneshvari Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Minimum age 18 and maximum age 80 years Candidate for hospitalization ( o2sat24 ?? Pao2/Fio2<300) The first 24 hours or 48 hours of hospitalization Signing up the informed consent form
Exclusion criteria
Exclusion criteria: Patients with heart block Patients with myocardial injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improve respiratory symptoms including shortness of breath and cough. Timepoint: Days 1 to 5 and at the end of the first week. Method of measurement: Questionnaire.;Blood o2 saturation. Timepoint: Just before and 1 hour after prescribe medication. Method of measurement: Pulse oximetry device. | — |
Secondary
| Measure | Time frame |
|---|---|
| C-reactive protein. Timepoint: C-reactive protein is measured daily for days 1 to 5. Method of measurement: Measurement of C-reactive protein is performed by a laboratory sample of blood taken from the patient.;Total number of lymphocytes. Timepoint: The total number of lymphocytes is measured daily for days 1 to 5. Method of measurement: Measurement of The total number of lymphocytes is performed by a laboratory sample of blood taken from the patient.;D-dimer test. Timepoint: The D-dimer test is measured daily for days one to five. Method of measurement: The D-dimer test is performed with a blood sample taken from the patient by a laboratory.;Ferritin. Timepoint: Ferritin is measured daily for days 1 to 5. Method of measurement: Measurement of ferritin is performed by a laboratory sample of blood taken from the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGuitti Pourdowlat
Shahid Beheshti University of Medical Sciences
Outcome results
None listed