Type 2 diabetes mellitus. Diabetes mellitus type 2 due to underlying condition
Conditions
Interventions
Intervention 1: Intervention group: In this group, subjects will use 100 grams of enriched-bread with pomegranate peel powder daily for breakfast and snacks for 12 weeks. Intervention 2: Control group
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age 40-60 Body mass index less than 30 Glycosylated hemoglobin less than 8 Willing to participate in the study, diagnosis of diabetes in the last 5 years Understanding the objectives of the study Written consent
Exclusion criteria
Exclusion criteria: No complications of diabetes Using insulin or oral agents inducing insulin secretion Smoking Pregnancy Lactation Taking antioxidant supplements within the last 3 months Having a history of cancer, cardiovascular disease, renal, hepatic and thyroid disorders before the intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?Effect of fortified-bread with pomegranate peel powder on FBS level. Timepoint: Before intervention and after 12 weeks consumption of fortified-bread with pomegranate peel powder. Method of measurement: Measurement by laboratory kit.;?Effect of fortified-bread with pomegranate peel powder on HbA1c level. Timepoint: Before intervention and after 12 weeks consumption of fortified-bread with pomegranate peel powder. Method of measurement: Measurement by chromatography.;?Effect of fortified-bread with pomegranate peel powder on insulin level. Timepoint: Before intervention and after 12 weeks consumption of fortified-bread with pomegranate peel powder. Method of measurement: Measurement by laboratory kit.;?Effect of fortified-bread with pomegranate peel powder on lipid profile level. Timepoint: Before intervention and after 12 weeks consumption of fortified-bread with pomegranate peel powder. Method of measurement: Measurement by laboratory kit.;?Effect of fortified-bread with pomegranate peel powder on Malon dealdehyde level. Timepoint: Before intervention and after 12 weeks consumption of fortified-bread with pomegranate peel powder. Method of measurement: Measurement by laboratory kit.;?Effect of fortified-bread with pomegranate peel powder on total antioxidant capacity level. Timepoint: Before intervention and after 12 weeks consumption of fortified-bread with pomegranate peel powder. Method of measurement: Measurement by laboratory kit.;C-reactive protein measurement with high sensitivity. Timepoint: Before intervention and after 12 weeks consumption of fortified-bread with pomegranate peel powder. Method of measurement: Measurement by laboratory kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression, anxiety and stress scales. Timepoint: Before intervention and after 12 weeks consumption of fortified bread with pomegranate peel powder. Method of measurement: Questionnaire.;Weight. Timepoint: Before intervention and after 12 weeks consumption of fortified bread with pomegranate peel powder. Method of measurement: scales.;Waist. Timepoint: Before intervention and after 12 weeks consumption of fortified bread with pomegranate peel powder. Method of measurement: Measuring meter.;Blood pressure. Timepoint: Before intervention and after 12 weeks consumption of fortified bread with pomegranate peel powder. Method of measurement: Blood pressure measuring device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Amani
Esfahan University of Medical Sciences
Outcome results
None listed