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effect of tranxamic acid on blood loss and need to transfusion in pelvic surgery

the effect of systemic and local injection of tranxamic acid on blood loss and need to transfusion in acetabulum surgery (Transverse, T Type and associated fracture)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191208045664N1
Enrollment
100
Registered
2019-12-19
Start date
2020-01-21
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acetabulum fracture. Fracture of acetabulum

Interventions

Intervention 1: Intervention group: Before surgical excision of this group, they will be infused with 1 gram of tranexamic acid dissolved in 100 ml of normal saline. 3 grams of tranexamic acid dissolv

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: patient over 18 year's old with T Type, Transverse and associated acetabular fracture

Exclusion criteria

Exclusion criteria: sensitive to tranxamic acid history of thrombotic disease coagulopathy disorder renal and hepatic function disorder patient with multi fracture who need multiple surgery history of CVA history of coronary stent Patients treated with anticoagulants massive transfusion before surgery sensitive to drugs patients treat with anticoagulats

Design outcomes

Primary

MeasureTime frame
Hemoglobin level. Timepoint: before surgery, 24 and 48he after surgery. Method of measurement: with automatic cell counter in laboratory.;Deep vein thrombosis. Timepoint: 3 weeks after surgery. Method of measurement: with color doppler sonography by the radiologist.;Bleeding volume. Timepoint: during and after surgery. Method of measurement: The volume of the suction tank, the number of gases-stained with blood, and bleeding of the surgery field. volume of the hemovak drain after surgery.;Blood transfuion. Timepoint: Before surgery; after 24 and 48hr of surgery. Method of measurement: According to Hb level.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAliasghar Tanha

Tabriz University of Medical Sciences

Tanha_med@yahoo.com+98 21 3608 0425

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026