secondary retinal detachment. Retinal detachment with retinal break
Conditions
Interventions
Intervention 1: Intervention Group: Use of Atorvastatin 40 mg (Actover Pharmaceutical Company) daily for 3 months after successful vitrectomy or scleral buckling surgery for retinal detachment. Interv
Sponsors
Vice Chancellor for Research, Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: age>40 primary attachment following PPV with silicon oil or sf6 tamponade vs scleral buckle regular follow up all of the surgery was done with a single experienced surgeon in a single center
Exclusion criteria
Exclusion criteria: combined RD recurrent RD RRD associated with giant tear Secondary RD due to other than PVR intraoperative complications like vitreous or suprachoroidal hemorrhages Other concomitant eye diseases affecting the retina including glaucoma, CSR, acquired and congenital retinal dystrophies, etc. PVRc lactation and pregnancy systemic steroid use Taking different medications that can interfere with statin use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Secondary retinal detachment. Timepoint: 1 day, 1 week and 1,3 and 6 months after the surgery. Method of measurement: examinations and OCT imaging. | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparing the rate of retinal detachment in groups of using statin and using placebo. Timepoint: day 1, week 1, month 1,3 and 6. Method of measurement: slit lamp examination and OCT. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Abdi
Iran University of Medical Sciences
Outcome results
None listed