Effects of Spirulina supplementation on ulcerative colitis patients

Effect of Spirulina supplement (Arthrospira platensis) on disease activity indices, quality of life, mood, fatigue, serum antioxidant status and serum pentraxin 3 levels in patients with ulcerative colitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191204045612N1

Enrollment

Registered

2020-01-15

Start date

2020-01-04

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis patients. Ulcerative colitis, unspecified

Interventions

Intervention 1: Intervention group: People entering the study will have mild or moderate level of ulcerative colitis, ranging in age from 18 to 65 years old (n=40). The group of patients will receive

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with mild to moderate ulcerative colitis in the age range of 18 to 65 years

Exclusion criteria

Exclusion criteria: Patients with severe ulcerative colitis Individuals in pregnancy or breastfeeding condition. Taking antidepressants and anxiety medications. Taking antioxidant and omega-3 supplements in the last three months. Smokers or alcohol consumers. Patients with kidney, liver, thyroid and parathyroid, gastrointestinal and heart disease and cancer disease.

Design outcomes

Primary

Measure	Time frame
Pentraxin 3. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Eliza kit.;Total antioxidant capacity. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Diagnostic kit.;Malondialdehyde. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Diagnostic kit.;Superoxide dismutase. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Diagnostic kit.;Erythrocyte Sedimentation Rate. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Measurement of erythrocyte sedimentation rate.;Disease activity indices. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: SCCAI questionnaire.	—

Measure

Time frame

Pentraxin 3. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Eliza kit.;Total antioxidant capacity. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Diagnostic kit.;Malondialdehyde. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Diagnostic kit.;Superoxide dismutase. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Diagnostic kit.;Erythrocyte Sedimentation Rate. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: Measurement of erythrocyte sedimentation rate.;Disease activity indices. Timepoint: Before intervention and 8 weeks after initiation of Spirulina supplementation. Method of measurement: SCCAI questionnaire.

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Secondary

Measure	Time frame
Weight. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Use scales.;Body mass index. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Calculation.;Waist. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: measurement.;Neck circumference. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Measurement.;Hip circumference. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Measurement.;Blood pressure. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Measurement.;Dietary intake. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: 24-h recall.;Fatigue. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: FSS questionnaire.;Physical activity. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: IPAQ questionnaire.;Quality of life. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: SIBDQ-9 questionnaire.;Sleep Quality. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Pittsburgh Sleep Quality Questionnaire.;Sleep duration. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Pittsburgh Sleep Quality Questionnaire.;Subjective sleep quality. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Pittsburgh Sleep Quality Questionnaire.;Sleep latency. Timepoint: Before intervention and 8 we	—

Measure

Time frame

Weight. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Use scales.;Body mass index. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Calculation.;Waist. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: measurement.;Neck circumference. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Measurement.;Hip circumference. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Measurement.;Blood pressure. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Measurement.;Dietary intake. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: 24-h recall.;Fatigue. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: FSS questionnaire.;Physical activity. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: IPAQ questionnaire.;Quality of life. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: SIBDQ-9 questionnaire.;Sleep Quality. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Pittsburgh Sleep Quality Questionnaire.;Sleep duration. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Pittsburgh Sleep Quality Questionnaire.;Subjective sleep quality. Timepoint: Before intervention and 8 weeks after initiation of spirulina supplementation. Method of measurement: Pittsburgh Sleep Quality Questionnaire.;Sleep latency. Timepoint: Before intervention and 8 we

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad hassan entezari

Esfahan University of Medical Sciences

entezari@hlth.mui.ac.ir009836680048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026