Skip to content

Comparison of midazolam – propofol versus midazolam – ketamin in sedative endoscopy in out patients

Comparison of midazolam – propofol versus midazolam – ketamin in sedative endoscopy in out patients since April until the end of November 2019 at the Ahvaz Imam Khomeini Hospital

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191201045566N1
Enrollment
78
Registered
2020-09-06
Start date
2019-09-30
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endoscopy.

Interventions

Intervention 1: Intervention group: Both groups were given fentanyl at a dose of 0.5 micrograms per kilogram. In group A, midazolam was administered intravenously at a rate of 0.5 micrograms per kilog

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: All endoscopic patients Age 20 to 60 years Weight 55 to 85 kg Being in ASA class one or two

Exclusion criteria

Exclusion criteria: Blood pressure history Diabetes Respiratory failure Liver problem Kidney problem Addiction Heart disease Drug allergy

Design outcomes

Primary

MeasureTime frame
Comparison of recovery time in patients between the two groups of midazolam-propofol with midazolam-ketamine in patients undergoing outpatient endoscopy. Timepoint: From the time the procedure was completed to the patient's alertness and appropriate response to questions, recovery time was considered (every 30 seconds, recovery was assessed). Method of measurement: Less than 5 minutes fast, between 5-10 minutes medium and more than 10 minutes slow recovery.;Comparison of hemodynamic changes in the two groups of midazolam-propofol with midazolam-ketamine in patients undergoing outpatient endoscopy. Timepoint: Vital signs (including heart rate, systolic and diastolic blood pressure, and oxygen saturation) before, and during, induction. Method of measurement: Heart rate per minute and systolic and diastolic blood pressure based on millimeters of mercury and arterial blood oxygen saturation.;Age, sex and weight in patients in the two groups of midazolam - propofol with midazolam - ketamine in patients undergoing outpatient endoscopy. Timepoint: On arrival. Method of measurement: Age based on number of years of life and weight based on kg and sex based on phenotype.;Sedation. Timepoint: From the moment of injection and during injection and after waking up. Method of measurement: Based on the Ramsey variable.;Comparison of nausea and vomiting in two groups of midazolam - propofol with midazolam - ketamine in patients undergoing outpatient endoscopy. Timepoint: From the end of the procedure to the time of leaving the recovery. Method of measurement: Visual analoge scale.;Comparison of postoperative pain in patients in two groups of midazolam-propofol with midazolam-ketamine in patients undergoing outpatient endoscopy. Timepoint: At the beginning of the procedure, the end of the procedure and one hour after the end of the procedure. Method of measurement: Ambesh score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Reza Baqbanian

Ahvaz University of Medical Sciences

baghbanian-r@ajums.ac.ir+98 61 3222 0168

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026