Effect of ondansetron alone on brain contusion

The evaluation of effect of ondansetron and dexamethasone combination versus ondansetron alone on treatment of nausea and vomiting in patient with minor head trauma

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191127045526N1

Enrollment

Registered

2020-04-12

Start date

2020-01-21

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Minor head trauma.

Interventions

Intervention 1: Intervention group: Ondansetron plus placebo group. In this group patients once received ondansetron 4mg plus placebo and then after one hour, patients were examined for nausea or vomi

Eligibility

Sex/Gender

All

Age

3 Years to No maximum

Inclusion criteria

Inclusion criteria: Head trauma with GCS>14 Head trauma with vomiting

Exclusion criteria

Exclusion criteria: Patients with shock signes patients with gastrointestinal disease causing nausea

Design outcomes

Primary

Measure	Time frame
Nausa vomiting treatment. Timepoint: 15 30 60 minutes after drug injection. Method of measurement: Patient evaluation in times15 30 60 minutes after drug.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Gholamreza Kargar

Zahedan University of Medical Sciences

Kargar98@zaums.ac.ir0098 54 3223001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026