Effect of Nano hydroxyapatite_containing tooth paste on the health of the enamel during orthodontic treatment.

The effect of Nano hydroxyapatite_containing tooth paste on enamel demineralization during the first six months of fixed orthodontic treatment- A triple-blind randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191127045518N2

Enrollment

Registered

2021-09-13

Start date

2021-09-23

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enamel demineralization, Nano hydroxyapatite, Fixed orthodontic treatment.

Interventions

Intervention 1: Intervention group: The teeth will be etched at the bracket base area with 37% phosphoric acid for 15 seconds, rinsed, and dried. Transbond XT Adhesive Primer and Transbond XT Adhesive

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Need for comprehensive orthodontic treatment by fixed appliances at least in the upper arch Permanent dentition No plaque accumulation or gingival inflammation before bracket bonding Good general health

Exclusion criteria

Exclusion criteria: Patients with smoking habit Patients with tooth anomalies Patients with active dental caries

Design outcomes

Primary

Measure	Time frame
The amount of enamel demineralization is measured by the number indicated by the DIAGNOdent device. Timepoint: The enamel demineralization will be recorded 3 times during the first 6 months of fixed orthodontic treatment. At the start of the study and 3, 6 months during the treatment. Method of measurement: Evaluating by DIAGNOdent device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmadreza Sardarian

Shiraz University of Medical Sciences

sardarian@sums.ac.ir+98 917 718 8859

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026