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comparison of the effect of Ketorolac and Betamethasone injection on post complications of third molar surgery

comparison of the effect of Ketorolac and Betamethasone injection on post complications of third molar surgery (A clinical trial)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191127045516N6
Enrollment
108
Registered
2022-02-26
Start date
2022-02-24
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

impacted teeth. Impacted teeth

Interventions

Intervention 1: Intervention group 1: A single intramuscular injection of 3mg betamethasone LA in 1mL (manufactured by Exir Pharmaceutical Company) in the master muscle immediately after injection of

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Physical health (ASA I or II) free of infection and pericoronitis. the presence of a third mandibular molars whose occlusion is confirmed by panoramic radiography age18 to 40 years old

Exclusion criteria

Exclusion criteria: Concomitant use of antibiotics and nonsteroidal anti-inflammatory drugs, salicylates, anticoagulants, anticonvulsants, and valprates is due to interaction with the injectable substance (ketorolac). Current use of any of these substances in the past month (drugs, alcohol, opium, smoking) Someone who has smoked at least two cigarettes a day in the past month Difficulty of surgery based on Pell and Gregory classification (Winter classification). allergies to the drugs used in this study Diseases that interfere with wound healing such as systemic diseases such as diabetes, hypertension, gastrointestinal diseases, kidney and lung and heart diseases, pregnancy.

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: second and seventh day after surgery. Method of measurement: visual analogue scale.;Swelling. Timepoint: second and seventh day after surgery. Method of measurement: visual analogue scale.;Trismus. Timepoint: the second and seventh day after surgery. Method of measurement: Maximum mouth opening limitation less than 35 mm.;Surgery difficulty. Timepoint: before the surgery. Method of measurement: Using panoramic radiography based on tooth position angle, depth and position relative to Ramos mandible - Based on panoramic radiographic classification (Pell and Gregory classification, Winter classifocation) -.;Patient general satisfaction. Timepoint: the second and seventh day after surgery. Method of measurement: visual analogue scale.;Maximum mouth opening. Timepoint: beofre the surgery and second and seventh day after surgery. Method of measurement: interincisal distance between mandibular and maxillary central teeth.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Nazari

Kermanshah University of Medical Sciences

Nazari.hamed67@gmail.com+98 83 3729 6591

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026