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Comparison of the effectiveness of Betamethasone LA injection into the masseter and medial pterygoid muscles in preventing the post-operative complications after mandibular third molar surgery

Comparison of the effectiveness of Betamethasone LA injection into the masseter and medial pterygoid muscles in preventing the post-operative complications after mandibular third molar surgery

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191127045516N5
Enrollment
90
Registered
2021-10-11
Start date
2021-10-09
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: severity of pain. Condition 2: Trismus. Condition 3: swelling. Condition 4: paresthesia. Acute pain, not elsewhere classified Other primary disorders of muscles Localized swelling, mass and lump, unspecified Disturbances of skin sensation

Interventions

Intervention 1: Intervention group:1: injection of 1mL ampoule of Betamethasone LA in to the internal pterygoid muscle immediately after anesthesia injection. Intervention 2: Intervention group 2: inj

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: ASA I or II health status. presence of a impacted mandibular third molar confirmed by a panoramic image absence of the mandibular third molar infection and pericoronitis The patient is ready to take part in the study and sign the testimonial

Exclusion criteria

Exclusion criteria: History of underlying diseases affecting the wound healing process like systemic diseases(diabetes,high blood pressure,gastrointestinal system diseases,kidney disorders,heart and lung diseases) current consumption of drugs,alcohol,opiums(consumption of any of these substances during the last month) smoking(someone who has smoked at least two cigarettes a day during the last month) recent consumption of anti- inflammatory drugs and antibiotics pregnant women any allergies or Hypersensitivities to the drugs used in this study

Design outcomes

Primary

MeasureTime frame
Severity of pain. Timepoint: before surgery,2 and 7 days later. Method of measurement: Visual Analogue Scale(VAS).;Swelling. Timepoint: 2 and 7 days after surgery. Method of measurement: Visual Analogue Scale(VAS).;General satisfaction. Timepoint: 2 and 7 days after surgery. Method of measurement: Visual Analogue Scale(VAS).;Trismus. Timepoint: 2 and 7 days after surgery. Method of measurement: Restrictions on opening the mouth(mild,moderate,severe).;Paresthesia. Timepoint: 2 and 7 days after surgery. Method of measurement: yes/no.;Maximum opening of the mouth. Timepoint: before surgery,2 and 7 days later. Method of measurement: by a ruler(0-50 millimetre).;Difficulty of the surgery. Timepoint: Before surgery. Method of measurement: according to panoramic radiograph based on spatial direction,depth and ramus relationship(easy,moderate,difficult).

Secondary

MeasureTime frame
Number of analgesics taken. Timepoint: 2 and 7 days after surgery. Method of measurement: number(0-100).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Nazari

Kermanshah University of Medical Sciences

Nazari.hamed67@gmail.com+98 83 3729 6591

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026