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The effect of Chitosan biodegradable scaffold in prevention of extracted tooth dry socket

Evaluation of the effect of Chitosan biodegradable scaffold in prevention of alveolar osteitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191127045516N4
Enrollment
176
Registered
2021-01-11
Start date
2021-01-20
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar osteitis. Alveolitis of jaws

Interventions

Intervention 1: Intervention group: Chitosan biodegradable scaffold is placed in the sockets of the extracted teeth after surgery. (The process of making scaffold is done by using chitosan polymer whi

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients in need of surgical extraction of the mandibular third molar who refer to oral surgery department of Kermanshah dental school Patients with risk factors for alveolar osteitis (history of pericoronitis, smoking, use of OCPs, history of alveolar osteitis)

Exclusion criteria

Exclusion criteria: Surgical complications in surgeon's opinion Antibiotic therapy regimen Patients' unwillingness to cooperate with the trial Loss to follow up

Design outcomes

Primary

MeasureTime frame
Incidence of alveolar osteitis after surgical extraction of mandibular impacted third molars. Timepoint: 3rd and 7th days after surgery. Method of measurement: Clinical diagnosis of alveolar osteitis by an experienced oral and maxillofacial surgeon regarding the signs and symptoms including: uncontrollable pain with analgesics between the first and third days to the week after tooth extraction with one or a combination of these signs: absence or insufficient blood clot in the socket, Detritus, exposed alveolar bone with or without halitosis.

Secondary

MeasureTime frame
Pain intensity after surgery. Timepoint: 3rd and 7th days after surgery. Method of measurement: Using Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Nazari

Kermanshah University of Medical Sciences

hamed.nazari@kums.ac.ir+98 83 3729 6591

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026