The prophylactic effect of Sumatriptan on pain following plastic nose surgery

The Effect of a Single 100 milligram Preoperative Dose of Sumatriptan on Postoperative Pain in Rhinoplasty

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191127045516N1

Enrollment

Registered

2019-12-12

Start date

2020-01-07

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-operative pain after rhinoplasty. G89.1

Interventions

Intervention 1: Intervention group: 1 hour prior to surgery, patients take a 100mg Sumatriptans tablets orally with 100 cc drinking water. Intervention 2: Control group: 1 hour prior to surgery, patie

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult individuals volunteering for rhinoplasty with ASA I status.

Exclusion criteria

Exclusion criteria: History of previous or present systemic diseases Hypersensitivity to Triptans Undergoing other surgical operations at the same time of rhinoplasty

Design outcomes

Primary

Measure	Time frame
Severity of postoperative pain. Timepoint: at 2,4,6,12,24 hours after the end of operation. Method of measurement: using the Visual Analogue Scale(VAS).	—

Secondary

Measure	Time frame
Nausea and vomiting. Timepoint: 24 hours after surgery. Method of measurement: yes/no.;Constipation. Timepoint: 24 hours after surgery. Method of measurement: yes/no.;Drowsiness. Timepoint: 24 hours after surgery. Method of measurement: yes/no.;Difficulty concentrating. Timepoint: 24 hours after surgery. Method of measurement: yes/no.;Dry mouth. Timepoint: 24 hours after surgery. Method of measurement: yes/no.	—

Measure

Time frame

Nausea and vomiting. Timepoint: 24 hours after surgery. Method of measurement: yes/no.;Constipation. Timepoint: 24 hours after surgery. Method of measurement: yes/no.;Drowsiness. Timepoint: 24 hours after surgery. Method of measurement: yes/no.;Difficulty concentrating. Timepoint: 24 hours after surgery. Method of measurement: yes/no.;Dry mouth. Timepoint: 24 hours after surgery. Method of measurement: yes/no.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Nazari

Kermanshah University of Medical Sciences

hamed.nazari@kums.ac.ir+98 83 3729 6591

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026