The effects of hypo-caloric and full-caloric enteral feeding on metabolic stress indices of patients with multiple trauma, during the first week of admission in the general intensive care unit

The effects of hypo-caloric and full-caloric enteral feeding on metabolic stress indices of patients with multiple trauma, during the first week

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191124045482N1

Enrollment

Registered

2019-12-28

Start date

2020-01-05

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

multiple truama. Injury, poisoning and certain other consequences of external causes

Interventions

Intervention 1: Intervention group: Patients in the intervention group will receive Hypocaloric diet. Subjects of hypocaloric diet group will receive 40 -30 percent of calculated calorie by using ind

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: age between 18-65 years Gastrointestinal tract with normal function and indications of Enteral Nutrition Diagnosis of moderate to severe trauma based on GCS (4-14) Enteral ability to feed in the first 24 to 48 hours of admission Completion of informed consent form from patients' first-degree reletives

Exclusion criteria

Exclusion criteria: failure to start enteral nutrition during the first 48 hours of admission Presence Cancer, diabetes, and cardiovascular disease pregnancy Patients who are less than 96 hours in intensive care unit

Design outcomes

Primary

Measure	Time frame
24 hours urea urine. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Triglyceride. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Serum lactate. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Blood Glucose. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Body temperature. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Rectal temperature measurement using mercury thermometer.;Resting energy expenditures. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Indirect calorimetric device.	—

Measure

Time frame

24 hours urea urine. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Triglyceride. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Serum lactate. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Blood Glucose. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Body temperature. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Rectal temperature measurement using mercury thermometer.;Resting energy expenditures. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Indirect calorimetric device.

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Secondary

Measure	Time frame
Mid arm circumference. Timepoint: At the baseline and 14 days after starting intervention. Method of measurement: Measuring meters.;Gastrointestinal intolerance. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Calorie intake. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Protein intake. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Number of hospital admissions days. Timepoint: Followed for 28 days. Method of measurement: questionnaire.	—

Measure

Time frame

Mid arm circumference. Timepoint: At the baseline and 14 days after starting intervention. Method of measurement: Measuring meters.;Gastrointestinal intolerance. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Calorie intake. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Protein intake. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Number of hospital admissions days. Timepoint: Followed for 28 days. Method of measurement: questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoya Ranjbar Miri

Mashhad University of Medical Sciences

ranjbarr1@mums.ac.ir+98 51 3882 7034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026