Breast cancer. Malignant neoplasm of breast
Conditions
Interventions
Intervention group: During breast-conserving surgery, patients will be treated with INTRABEAM 50-kV X-ray source at a dose of 20 Gy. Postoperatively, patients will receive systemic treatment according
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: Pathologic diagnosis of invasive ductal breast cancer Breast cancer with size less than or equal to 3 cm No lymph node involvement No distant metastases
Exclusion criteria
Exclusion criteria: Pregnancy Lactation Active collagen vascular diseases such as scleroderma Previous radiotherapy in diseases such as Hodgkin's lymphoma Multifocal breast cancer Presence of distant metastasis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease free survival. Timepoint: Two years after completion of treatment. Method of measurement: Physical examination and breast imaging.;Overall survival. Timepoint: Two years after completion of treatment. Method of measurement: Follow up of patient.;Skin toxicity. Timepoint: Two years after completion of treatment. Method of measurement: Physical examination based on toxicity criteria of the Radiation Therapy Oncology Group and the European Organization for Research and Treatment of Cancer.;Subcutaneous toxicity. Timepoint: Two years after completion of treatment. Method of measurement: Physical examination based on toxicity criteria of the Radiation Therapy Oncology Group and the European Organization for Research and Treatment of Cancer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElyar Mousa Pour Shahi
Mashhad University of Medical Sciences
Outcome results
None listed