Evaluating the effect of hypertonic saline in edema

Evaluating the effect of hypertonic saline in edema of ICU patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191115045446N1

Enrollment

Registered

2020-01-01

Start date

2020-01-03

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Generalized edema. Generalized edema

Interventions

Intervention group: receiving 50 ml Hypertonic saline and 20 mg Furosemide TDS for 48 hours.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Admission patients in ICU who have more than 18 years old Patients that have 2+ edema or more

Exclusion criteria

Exclusion criteria: Sodium more than 155 Albumin less than 2 mg/dl Creatinine equal to or more than 1.5 mg/dl Hemodialysis patients Blood pressure more than 180/100 Norepinephrine dependent blood pressure

Design outcomes

Primary

Measure	Time frame
Patients in Intensive care unit with 2+ edema or more. Timepoint: entrance to study and 2 days after intervention. Method of measurement: Measuring of urine volume and edema.	—

Secondary

Measure	Time frame
APACHE II score. Timepoint: entrance to study. Method of measurement: APACHE II score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Sistanizad

Shahid Beheshti University of Medical Sciences

sistanizadm@sbmu.ac.ir+98218800087

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026