?Acne Vulgaris. Acne vulgaris (or simply acne) is a long-term skin disease that occurs when hair follicles become clogged with dead skin cells and oil from the skin. Acne is characterized by areas of blackheads, whiteheads, pimples, and greasy skin, and may result in sca
Conditions
Interventions
Intervention 1: Intervention group: Topical tretinoin formulation and Arctium Lappa topical formulation are applied once daily for three months on face skin. Intervention 2: Control group: Topical app
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
12 Years to 30 Years
Inclusion criteria
Inclusion criteria: Women and men aged 12-30 years with mild to moderate acne vulgaris Have signed the informed consent form
Exclusion criteria
Exclusion criteria: Pregnant or breastfeeding or planning to become pregnant Have a history of sensitivity to the components of the formulations used in the study Other skin diseases such as eczema that make it difficult to evaluate the response to treatment Have uncontrolled systemic disease They have Acne Conglobata Not taking the following drugs before starting the plan (topical anti-acne drugs for two weeks, oral antibiotics for one month, 12 weeks hormone therapy and 6 months oral retinoids).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne Complication. Timepoint: One month after intervention, two months after intervention, three months after intervention. Method of measurement: Based on acne lesion counting. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmirreza Entezari
Mashhad University of Medical Sciences
Outcome results
None listed