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Evaluation of the effect of HESA-A on the prevention and treatment of chemotherapy-induced nausea and vomiting

Evaluation of the effect of HESA-A on the prevention and treatment of chemotherapy-induced nausea and vomiting in Breast and Lung cancer patients Referring to Kashani Shahrekord Medical Education Center

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191111045398N1
Enrollment
98
Registered
2020-01-19
Start date
2019-06-22
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting after chemotherapy.

Interventions

Intervention group: In the intervention group, one 50 mg oral tablet every 5 hours before chemotherapy up to 5 days after chemotherapy.

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: The definitive diagnosis of cancer by a physician and pathologist Age 18-70 years One day chemotherapy courses or at least one chemistry course History of vomiting experience following previous chemistry sessions The normality of hematological and biochemical laboratory values Lack of concomitant radiotherapy with chemotherapy (total or upper abdominal) Absence of vomiting diseases such as chronic kidney failure, liver failure, gastrointestinal problems and hypertension Absence of coagulation problems and blood disorders such as severe thrombocytopenia Patient's informed consent

Exclusion criteria

Exclusion criteria: 1. Make allergies to medicines Use of other medicines or treatments other than the usual nausea and vomiting medications prescribed Problems and complications of gastrointestinal obstruction during the study Unwillingness to continue participating in

Design outcomes

Primary

MeasureTime frame
The number and severity of nausea and vomiting. Timepoint: Daily from 5 days before chemotherapy to 5 days after From chemotherapy. Method of measurement: Questionnaire for recording the number and severity of nausea and vomiting.

Secondary

MeasureTime frame
Quality of Life. Timepoint: Daily from 5 days before chemotherapy to 5 days after chemotherapy. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFateme Salehi Choliche

Shahre-kord University of Medical Sciences

f6493salehi@gmail.com+98 38 3224 1380

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026