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The effect of oral Zingiber officinale supplement in diabetic in hemodialysis patients with diabetes

Comparison of the effect of oral Zingiber officinale supplement and placebo on some inflammatory factors and lipid profile and anthropometric measures in diabetic hemodialysis patients: A double blind randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20191109045382N3
Enrollment
44
Registered
2020-07-17
Start date
2020-02-09
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic hemodialysis. Type 2 diabetes mellitus with diabetic chronic kidney disease

Interventions

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diabetic patients undergoing hemodialysis who have been on dialysis for at least 3 months Two or three dialysis sessions a week The duration of each session dialysis is 4 hours Patients who desire to enter the study Patients over 18 years of age

Exclusion criteria

Exclusion criteria: History of acute gastrointestinal disease History of Thyroid disorders History of gallstones Consumption of fish oil supplement Consumption steroid and non-steroidal anti-inflammatory drugs Consumption of Levothyroxine Consumption of Warfarin Consumption of antioxidant supplements History of ginger allergy Smoking

Design outcomes

Primary

MeasureTime frame
Cholestrol. Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Measurement of Cholesterol by enzymatic method.;Triglyceride. Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Measurement of Triglycerides by enzymatic method.;Low density lipoprotein (LDL). Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: LDL measurement by enzymatic method.;High density lipoprotein (HDL). Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Measurement of HDL by enzymatic method.;Anthropometric measure. Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Height measurement with a meter and weight measurement with a scale.;Level of high sensivity C-reactive protein (hs-CRP) inflammatory factor. Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Measurement of hs-CRP by immuno-turbidimetric method.;Level of Interleukine-6 (IL-6) inflammatory factor. Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Measurement of IL6 with ELISA kit.;Platelet lymphocyte ratio (PLR). Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Measurement of PLR by CBC test.;Neutrophil lymphocyte ratio (NLR). Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Measurement of NLR by CBC test.

Secondary

MeasureTime frame
Intake calories and macronutrients. Timepoint: At the beginning of the study and 8 weeks after intervention. Method of measurement: Recall and record food Questionnaires.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa veisi

Tabriz University of Medical Sciences

parisaveisi1995@gmail.com+98 41 3340 8619

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026