comparing the effect of two different doses of ondansetron on heart rate , blood pressure and blood oxygen saturation variation in caesarian surgery under spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20191109045371N1

Enrollment

Registered

2020-10-14

Start date

2020-03-20

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean section. Onset (spontaneous) of labor after 37 completed weeks of gestation but before 39 completed weeks gestation, with delivery by (planned) cesarean section

Interventions

Intervention 1: Intervention group 1: patients take 6 mg ondansetron. Intervention 2: Intervention group: patients take 8 mg ondansetron. Intervention 3: Control group: patients take 4cc distilled wat

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age between 18 to 45 years old ASA number 1 and 2 Patient is cesarian candida that term pregnancy Patient has no disease like hypertention Patient has no uncontrolled diabet Patient has no allergy to ondansetron or local anesthtic drug no forbid for spinal anesthesia Patient dosent use drugs which effect on HT35 receptor

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Befor operation and every 15 minute during operation and recovery. Method of measurement: mercury barometer.;Blood oxygen saturation. Timepoint: Befor operation and every 15 minute during operation and recovery. Method of measurement: puls oxymeter.;Heart rate. Timepoint: Befor operation and every 15 minute during operation and recovery. Method of measurement: puls oxymeter.	—

Measure

Time frame

Blood pressure. Timepoint: Befor operation and every 15 minute during operation and recovery. Method of measurement: mercury barometer.;Blood oxygen saturation. Timepoint: Befor operation and every 15 minute during operation and recovery. Method of measurement: puls oxymeter.;Heart rate. Timepoint: Befor operation and every 15 minute during operation and recovery. Method of measurement: puls oxymeter.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Reza Shetabi

Esfahan University of Medical Sciences

hamidshetabi@med.mui.ac.ir0098 31 3660048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026